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Insulin regulation of rat growth hormone gene transcription.

We have previously shown that insulin suppresses growth hormone (GH) messenger (m) RNA levels in rat pituitary cells. To further delineate the molecular mechanism of insulin action, the effect of insulin treatment on GH gene transcription rates was examined in GH3 pituitary cells grown in serum-free...

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Pubblicato in:J Clin Invest
Autori principali: Yamashita, S, Melmed, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3531235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112654
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