Fine Tuning of Ca(V)1.3 Ca(2+) Channel Properties in Adult Inner Hair Cells Positioned in the Most Sensitive Region of the Gerbil Cochlea

Hearing relies on faithful signal transmission by cochlear inner hair cells (IHCs) onto auditory fibres over a wide frequency and intensity range. Exocytosis at IHC ribbon synapses is triggered by Ca(2+) inflow through Ca(V)1.3 (L-type) Ca(2+) channels. We investigated the macroscopic (whole-cell) a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zampini, Valeria, Johnson, Stuart L., Franz, Christoph, Knipper, Marlies, Holley, Matthew C., Magistretti, Jacopo, Russo, Giancarlo, Marcotti, Walter, Masetto, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237458/
https://ncbi.nlm.nih.gov/pubmed/25409445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113750
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