PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis

The REGγ-proteasome serves as a short-cut for the destruction of certain intact mammalian proteins in the absence of ubiquitin-and ATP. The biological roles of the proteasome activator REGγ are not completely understood. Here we demonstrate that REGγ controls degradation of protein kinase A catalyti...

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Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Liu, Shuang, Lai, Li, Zuo, Qiuhong, Dai, Fujun, Wu, Lin, Wang, Yan, Zhou, Qingxia, Liu, Jian, Liu, Jiang, Li, Lei, Lin, Qingxiang, Creighton, Chad J., Costello, Myra Grace, Huang, Shixia, Jia, Caifeng, Liao, Lujian, Luo, Honglin, Fu, Junjiang, Liu, Mingyao, Yi, Zhengfang, Xiao, Jianru, Li, Xiaotao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237316/
https://ncbi.nlm.nih.gov/pubmed/24560667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.02.007
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