Misregulation of Rad50 expression in melanoma cells

DNA double-strand breaks are increased in human melanoma tissue as detected by histone H2AX phosphorylation1,2,3. We investigated two of the downstream effectors of DNA double-strand breaks, Rad50 and 53BP1 (tumor suppressor p53 binding protein 1), to determine if they are altered in human primary m...

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Gepubliceerd in:J Cutan Pathol
Hoofdauteurs: Avaritt, Nathan L., Owens, Richard, Larson, Signe K., Reynolds, Matthew, Byrum, Stephanie, Hiatt, Kim M., Smoller, Bruce R., Tackett, Alan J., Cheung, Wang L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237308/
https://ncbi.nlm.nih.gov/pubmed/22725639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0560.2012.01915.x
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