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Immune-modulating effects of alpha-1 antitrypsin
Alpha-1 antitrypsin (AAT) is a circulating serine protease inhibitor (serpin) that inhibits neutrophil elastase in the lung, and AAT deficiency is associated with early-onset emphysema. AAT is also a liver-derived acute phase protein that, in vitro and in vivo, reduces production of pro-inflammatory...
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Publicado no: | Biol Chem |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237306/ https://ncbi.nlm.nih.gov/pubmed/24854541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2014-0161 |
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