Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate

Loss of imprinting (LOI) is an epigenetic alteration involving loss of parental origin-specific expression at normally imprinted genes. A LOI for Igf2, a paracrine growth factor, is important in cancer progression. Epigenetic modifications may be altered by environmental factors. However, is not kno...

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Bibliografiska uppgifter
I publikationen:Cancer Res
Huvudupphovsmän: Fu, Vivian X., Dobosy, Joseph R., Desotelle, Joshua A., Almassi, Nima, Ewald, Jonathan A., Srinivasan, Rajini, Berres, Mark, Svaren, John, Weindruch, Richard, Jarrard, David F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237281/
https://ncbi.nlm.nih.gov/pubmed/18701505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1714
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