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Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31
Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 and suppresses gene expression by catalyzing histone H3 methylation on lysine 27. EZH2 is overexpressed in metastatic prostate cancer and has been shown to promote cell proliferation and metastasis. Here...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237267/ https://ncbi.nlm.nih.gov/pubmed/25341040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.454 |
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