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HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation

Acute myeloid leukemia (AML) is recognized as a complex disease of hematopoietic stem cell disorders, but its pathogenesis mechanisms, diagnosis, and treatment remain unclear. General histone deacetylase (HDAC) inhibitors have been used in blood cancers including AML, but the lack of gene specificit...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Huang, Y, Chen, J, Lu, C, Han, J, Wang, G, Song, C, Zhu, S, Wang, C, Li, G, Kang, J, Wang, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237257/
https://ncbi.nlm.nih.gov/pubmed/25341045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.433
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