Modulation of redox signaling promotes apoptosis in epithelial ovarian cancer cells

OBJECTIVE: Epithelial ovarian cancer (EOC) cells are known to be resistant to apoptosis through a mechanism that may involve alteration in their redox balance. NADPH oxidase is a major source of intracellular superoxide, which is converted to the less toxic product by superoxide dismutase (SOD). Sup...

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Pubblicato in:Gynecol Oncol
Autori principali: Jiang, Zhongliang, Fletcher, Nicole M., Ali-Fehmi, Rouba, Diamond, Michael P., Abu-Soud, Husam M., Munkarah, Adnan R., Saed, Ghassan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237166/
https://ncbi.nlm.nih.gov/pubmed/21620448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.04.051
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