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Sense codon emancipation for proteome-wide incorporation of noncanonical amino acids: rare isoleucine codon AUA as a target for genetic code expansion

One of the major challenges in contemporary synthetic biology is to find a route to engineer synthetic organisms with altered chemical constitution. In terms of core reaction types, nature uses an astonishingly limited repertoire of chemistries when compared with the exceptionally rich and diverse m...

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Detalhes bibliográficos
Publicado no:FEMS Microbiol Lett
Main Authors: Bohlke, Nina, Budisa, Nediljko
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237120/
https://ncbi.nlm.nih.gov/pubmed/24433543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1574-6968.12371
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