Characterization of a transthyretin (prealbumin) variant associated with familial amyloidotic polyneuropathy type II (Indiana/Swiss).

Amyloid fibrils were isolated from cardiac tissue of two brothers who died from familial amyloidotic polyneuropathy (FAP) type II. Sequence analysis on peptides derived from proteolytic cleavage with trypsin and fragmentation with cyanogen bromide reveal that the fibril subunit protein is derived fr...

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Pubblicato in:	J Clin Invest
Autori principali:	Dwulet, F E, Benson, M D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3760189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112675
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