Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4

The female hormone progesterone (P4) promotes the expansion of stem-like cancer cells in estrogen receptor (ER) and progesterone receptor (PR) positive breast tumors. The expanded tumor cells lose expression of ER and PR, express the tumor-initiating marker CD44, the progenitor marker cytokeratin 5...

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Publicat a:Oncogene
Autors principals: Cittelly, Diana M., Finlay-Schultz, Jessica, Howe, Erin N., Spoelstra, Nicole S., Axlund, Sunshine Daddario, Hendricks, Peter, Jacobsen, Britta M., Sartorius, Carol A., Richer, Jennifer K.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236860/
https://ncbi.nlm.nih.gov/pubmed/22751119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.275
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