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Deficiency of the pyruvate dehydrogenase component in pyruvate dehydrogenase complex-deficient human fibroblasts. Immunological identification.

A previously reported deficiency of "total" pyruvate dehydrogenase complex activity is further characterized. Dihydrolipoyl transacetylase (E2) and lipoamide dehydrogenase (E3) activities in the patient's fibroblasts were normal. Pyruvate dehydrogenase activity (E1) was 33% of that in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Ho, L, Hu, C W, Packman, S, Patel, M S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3091638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112651
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