Elevated epidermal growth factor receptor gene copy number and expression in a squamous carcinoma cell line.

The human epidermal growth factor (EGF) receptor is known to be homologous to the v-erb B oncogene protein of the avian erythroblastosis virus. Overexpression of the EGF receptor gene in A431 epidermoid carcinoma cells is due to gene amplification. In this study, a variety of squamous cell carcinoma...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Merlino, G T, Xu, Y H, Richert, N, Clark, A J, Ishii, S, Banks-Schlegel, S, Pastan, I
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2984254/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111770
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