Elevated epidermal growth factor receptor gene copy number and expression in a squamous carcinoma cell line.

The human epidermal growth factor (EGF) receptor is known to be homologous to the v-erb B oncogene protein of the avian erythroblastosis virus. Overexpression of the EGF receptor gene in A431 epidermoid carcinoma cells is due to gene amplification. In this study, a variety of squamous cell carcinoma...

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Bibliographic Details
Main Authors: Merlino, G T, Xu, Y H, Richert, N, Clark, A J, Ishii, S, Banks-Schlegel, S, Pastan, I
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC423669/
https://ncbi.nlm.nih.gov/pubmed/2984254
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