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Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle

BACKGROUND: Defects in skeletal muscle fatty acid oxidation have been implicated in the etiology of insulin resistance. Malonyl-CoA decarboxylase (MCD) has been a target of investigation because it reduces the concentration of malonyl-CoA, a metabolite that inhibits fatty acid oxidation. The in vivo...

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Vydáno v:BMC Biochem
Hlavní autoři: Rodriguez, Susana, Ellis, Jessica M, Wolfgang, Michael J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236586/
https://ncbi.nlm.nih.gov/pubmed/25152047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-15-20
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