Inhibition of collagen deposition in the extracellular matrix prevents the establishment of a stroma supportive of hematopoiesis in long-term murine bone marrow cultures.

Long-term production of murine hematopoietic cells in vitro is dependent on establishment of a complex microenvironment consisting of a variety of stromal cells and an extensive extracellular matrix which includes collagen, fibronectin, laminin, proteoglycans, and other undefined components adherent...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zuckerman, K S, Rhodes, R K, Goodrum, D D, Patel, V R, Sparks, B, Wells, J, Wicha, M S, Mayo, L A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423639/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3980732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111798
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