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Characterization of Albendazole-Randomly Methylated-β-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis

Albendazole is a benzimidazole carbamate extensively used in oral chemotherapy against intestinal parasites, due to its broad spectrum activity, good tolerance and low cost. However, the drug has the disadvantage of poor bioavailability due to its very low solubility in water; as a consequence, a ve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: García, Agustina, Leonardi, Darío, Vasconi, María D., Hinrichsen, Lucila I., Lamas, María C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236198/
https://ncbi.nlm.nih.gov/pubmed/25406084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113296
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