Characterization of Albendazole-Randomly Methylated-β-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis

Albendazole is a benzimidazole carbamate extensively used in oral chemotherapy against intestinal parasites, due to its broad spectrum activity, good tolerance and low cost. However, the drug has the disadvantage of poor bioavailability due to its very low solubility in water; as a consequence, a ve...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: García, Agustina, Leonardi, Darío, Vasconi, María D., Hinrichsen, Lucila I., Lamas, María C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236198/
https://ncbi.nlm.nih.gov/pubmed/25406084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113296
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