Regulator of G-Protein Signaling 18 Controls Both Platelet Generation and Function

RGS18 is a myeloerythroid lineage-specific regulator of G-protein signaling, highly expressed in megakaryocytes (MKs) and platelets. In the present study, we describe the first generation of a RGS18 knockout mouse model (RGS18-/-). Interesting phenotypic differences between RGS18-/- and wild-type (W...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Delesque-Touchard, Nathalie, Pendaries, Caroline, Volle-Challier, Cécile, Millet, Laurence, Salel, Véronique, Hervé, Caroline, Pflieger, Anne-Marie, Berthou-Soulie, Laurence, Prades, Catherine, Sorg, Tania, Herbert, Jean-Marc, Savi, Pierre, Bono, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236145/
https://ncbi.nlm.nih.gov/pubmed/25405900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113215
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