Role of the Inflammasome-Caspase1/11-IL-1/18 Axis in Cigarette Smoke Driven Airway Inflammation: An Insight into the Pathogenesis of COPD

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory airway disease often associated with cigarette smoke (CS) exposure. The disease is increasing in global prevalence and there is no effective therapy. A major step forward would be to understand the disease pathogenesis. The...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Eltom, Suffwan, Belvisi, Maria G., Stevenson, Christopher S., Maher, Sarah A., Dubuis, Eric, Fitzgerald, Kate A., Birrell, Mark A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236128/
https://ncbi.nlm.nih.gov/pubmed/25405768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112829
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