Tailoring Subunit Vaccine Immunity with Adjuvant Combinations and Delivery Routes Using the Middle East Respiratory Coronavirus (MERS-CoV) Receptor-Binding Domain as an Antigen

The development of an effective vaccine is critical for prevention of a Middle East respiratory syndrome coronavirus (MERS-CoV) pandemic. Some studies have indicated the receptor-binding domain (RBD) protein of MERS-CoV spike (S) is a good candidate antigen for a MERS-CoV subunit vaccine. However, h...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lan, Jiaming, Deng, Yao, Chen, Hong, Lu, Guangwen, Wang, Wen, Guo, Xiaojuan, Lu, Zhuozhuang, Gao, George F., Tan, Wenjie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236105/
https://ncbi.nlm.nih.gov/pubmed/25405618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112602
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