Lymphotoxin-LIGHT Pathway Regulates the Interferon Signature in Rheumatoid Arthritis

A subset of patients with autoimmune diseases including rheumatoid arthritis (RA) and lupus appear to be exposed continually to interferon (IFN) as evidenced by elevated expression of IFN induced genes in blood cells. In lupus, detection of endogenous chromatin complexes by the innate sensing machin...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bienkowska, Jadwiga, Allaire, Norm, Thai, Alice, Goyal, Jaya, Plavina, Tatiana, Nirula, Ajay, Weaver, Megan, Newman, Charlotte, Petri, Michelle, Beckman, Evan, Browning, Jeffrey L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236099/
https://ncbi.nlm.nih.gov/pubmed/25405351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112545
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