The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) entails a mesenchymal to epithelial transition (MET). While attempting to dissect the mechanism of MET during reprogramming, we observed that knockdown (KD) of the epithelial-to-mesenchymal transition (EMT) factor SNAI1 (SNAIL) p...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Unternaehrer, Juli J., Zhao, Rui, Kim, Kitai, Cesana, Marcella, Powers, John T., Ratanasirintrawoot, Sutheera, Onder, Tamer, Shibue, Tsukasa, Weinberg, Robert A., Daley, George Q.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235745/
https://ncbi.nlm.nih.gov/pubmed/25316190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.09.008
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