Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a “Bookmarking” Oncoprotein that Alters the Host Cell Epigenotype?

EBNA1, a nuclear protein expressed in all EBV-associated neoplasms is indispensable for the maintenance of the viral episomes in latently infected cells. EBNA1 may induce genetic alterations by upregulating cellular recombinases, production of reactive oxygen species (ROS) and affecting p53 levels a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pathogens
Main Authors: Niller, Hans Helmut, Minarovits, Janos
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2012
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235684/
https://ncbi.nlm.nih.gov/pubmed/25436603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens1010037
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