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Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the α5β1 integrin

Alterations in vascular structure and function are a central component of demyelinating disease. In addition to blood-brain barrier (BBB) breakdown, which occurs early in the course of disease, recent studies have described angiogenic remodeling, both in multiple sclerosis tissue and in the mouse de...

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Pubblicato in:Exp Neurol
Autori principali: Boroujerdi, Amin, Welser-Alves, Jennifer V., Milner, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235607/
https://ncbi.nlm.nih.gov/pubmed/24056042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.09.009
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