Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen

Targeting antigen to dendritic cells (DCs) is a powerful and novel strategy for vaccination. Priming or loading DCs with antigen controls whether subsequent immunity will develop and hence whether effective vaccination can be achieved. The goal of our present work was to increase the potency of DC-b...

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Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Saluja, Sandeep S, Hanlon, Douglas J, Sharp, Fiona A, Hong, Enping, Khalil, David, Robinson, Eve, Tigelaar, Robert, Fahmy, Tarek M, Edelson, Richard L
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235494/
https://ncbi.nlm.nih.gov/pubmed/25419128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S66639
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