Clozapine promotes glycolysis and myelin lipid synthesis in cultured oligodendrocytes

Clozapine displays stronger systemic metabolic side effects than haloperidol and it has been hypothesized that therapeutic antipsychotic and adverse metabolic effects of these drugs are related. Considering that cerebral disconnectivity through oligodendrocyte dysfunction has been implicated in schi...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Steiner, Johann, Martins-de-Souza, Daniel, Schiltz, Kolja, Sarnyai, Zoltan, Westphal, Sabine, Isermann, Berend, Dobrowolny, Henrik, Turck, Christoph W., Bogerts, Bernhard, Bernstein, Hans-Gert, Horvath, Tamas L., Schild, Lorenz, Keilhoff, Gerburg
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235405/
https://ncbi.nlm.nih.gov/pubmed/25477781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00384
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