Clozapine promotes glycolysis and myelin lipid synthesis in cultured oligodendrocytes

Clozapine displays stronger systemic metabolic side effects than haloperidol and it has been hypothesized that therapeutic antipsychotic and adverse metabolic effects of these drugs are related. Considering that cerebral disconnectivity through oligodendrocyte dysfunction has been implicated in schi...

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Pubblicato in:Front Cell Neurosci
Autori principali: Steiner, Johann, Martins-de-Souza, Daniel, Schiltz, Kolja, Sarnyai, Zoltan, Westphal, Sabine, Isermann, Berend, Dobrowolny, Henrik, Turck, Christoph W., Bogerts, Bernhard, Bernstein, Hans-Gert, Horvath, Tamas L., Schild, Lorenz, Keilhoff, Gerburg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235405/
https://ncbi.nlm.nih.gov/pubmed/25477781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00384
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