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Metal specificity of cyanobacterial nickel-responsive repressor InrS: cells maintain zinc and copper below the detection threshold for InrS

InrS is a Ni(II)-responsive, CsoR/RcnR-like, DNA-binding transcriptional repressor of the nrsD gene, but the Ni(II) co-ordination sphere of InrS is unlike Ni(II)-RcnR. We show that copper and Zn(II) also bind tightly to InrS and in vitro these ions also impair InrS binding to the nrsD operator-promo...

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Библиографические подробности
Опубликовано в: :Mol Microbiol
Главные авторы: Foster, Andrew W, Pernil, Rafael, Patterson, Carl J, Robinson, Nigel J
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235346/
https://ncbi.nlm.nih.gov/pubmed/24666373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12594
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