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17β-estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo

Exogenous 17β-estradiol (E2) accelerates the progression of ovarian cancer in the transgenic tgCAG-LS-TAg mouse model of the disease. We hypothesized that E2 has direct effects on ovarian cancer cells and this study was designed to determine the molecular mechanisms by which E2 accelerates ovarian t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Cancer
Hauptverfasser: Laviolette, Laura A, Hodgkinson, Kendra M, Minhas, Neha, Perez-Iratxeta, Carol, Vanderhyden, Barbara C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235304/
https://ncbi.nlm.nih.gov/pubmed/24469735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28741
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