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Modulation of heparin cofactor II activity by histidine-rich glycoprotein and platelet factor 4.

Heparin cofactor II is a plasma protein that inhibits thrombin rapidly in the presence of either heparin or dermatan sulfate. We have determined the effects of two glycosaminoglycan-binding proteins, i.e., histidine-rich glycoprotein and platelet factor 4, on these reactions. Inhibition of thrombin...

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Pubblicato in:J Clin Invest
Autori principali: Tollefsen, D M, Pestka, C A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3838317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111725
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