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Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells

BACKGROUND: Flotillin-1 and flotillin-2 are two homologous and ubiquitously expressed proteins that are involved in signal transduction and membrane trafficking. Recent studies have reported that flotillins promote breast cancer progression, thus making them interesting targets for breast cancer tre...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kurrle, Nina, Ockenga, Wymke, Meister, Melanie, Völlner, Frauke, Kühne, Sina, John, Bincy A, Banning, Antje, Tikkanen, Ritva
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235219/
https://ncbi.nlm.nih.gov/pubmed/24304721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-575
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