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Noncanonical G-Protein-Dependent Modulation of Osteoclast Differentiation and Bone Resorption Mediated by Pasteurella multocida Toxin

Pasteurella multocida toxin (PMT) induces atrophic rhinitis in animals, which is characterized by a degradation of nasal turbinate bones, indicating an effect of the toxin on bone cells such as osteoblasts and osteoclasts. The underlying molecular mechanism of PMT was defined as a persistent activat...

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發表在:mBio
Main Authors: Strack, Julia, Heni, Hannah, Gilsbach, Ralf, Hein, Lutz, Aktories, Klaus, Orth, Joachim H. C.
格式: Artigo
語言:Inglês
出版: American Society of Microbiology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235216/
https://ncbi.nlm.nih.gov/pubmed/25389180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02190-14
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