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Age-associated decrease in global DNA methylation in patients with major depression

BACKGROUND: Evidence has supported a role of DNA methylation in the pathophysiology of mood disorders. The purpose of the current study is to examine 5-methylcytosine (5-mc) and 5-hydroxymethylcytosine (5-hmc) levels in patients with major depressive disorder (MDD) at different disease states. METHO...

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Detalhes bibliográficos
Publicado no:Neuropsychiatr Dis Treat
Main Authors: Tseng, Ping-Tao, Lin, Pao-Yen, Lee, Yu, Hung, Chi-Fa, Lung, For-Wey, Chen, Cheng-Sheng, Chong, Mian-Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235206/
https://ncbi.nlm.nih.gov/pubmed/25419133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S71997
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