let-7 miRNAs Can Act through Notch to Regulate Human Gliogenesis

It is clear that neural differentiation from human pluripotent stem cells generates cells that are developmentally immature. Here, we show that the let-7 plays a functional role in the developmental decision making of human neural progenitors, controlling whether these cells make neurons or glia. Th...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Patterson, M., Gaeta, X., Loo, K., Edwards, M., Smale, S., Cinkornpumin, J., Xie, Y., Listgarten, J., Azghadi, S., Douglass, S.M., Pellegrini, M., Lowry, W.E.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235151/
https://ncbi.nlm.nih.gov/pubmed/25316189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.015
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