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Declining sensitivity to interleukin 3 of murine multipotential hemopoietic progenitors during their development. Application to a culture system that favors blast cell colony formation.

When spleen cells of 5-fluorouracil (5-FU)-treated mice were cultured in the presence of interleukin 3 (IL-3), most colonies revealed IL-3 concentration-dependent colony formation except for mast cell colonies and blast cell colonies. While most colonies were smaller in lower concentrations of IL-3,...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Koike, K, Ihle, J N, Ogawa, M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3081577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112387
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