Abnormal antithrombin III with defective serine protease binding (antithrombin III "Denver").

A hereditary (three family members) deficiency of antithrombin III (AT-III) in which AT-III antigen (AT-III ag) is normal in spite of low heparin cofactor and antithrombin activity is described. Plasma levels were: AT-III ag, 0.92-0.96 U/ml; AT-III heparin cofactor activity, 0.54-0.62 U/ml; progress...

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Pubblicato in:	J Clin Invest
Autori principali:	Sambrano, J E, Jacobson, L J, Reeve, E B, Manco-Johnson, M J, Hathaway, W E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3512602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112386
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