Evaluation of the Efficacy & Biochemical Mechanism of Cell Death Induction by Piper longum Extract Selectively in In-Vitro and In-Vivo Models of Human Cancer Cells

BACKGROUND: Currently chemotherapy is limited mostly to genotoxic drugs that are associated with severe side effects due to non-selective targeting of normal tissue. Natural products play a significant role in the development of most chemotherapeutic agents, with 74.8% of all available chemotherapy...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ovadje, Pamela, Ma, Dennis, Tremblay, Phillip, Roma, Alessia, Steckle, Matthew, Guerrero, Jose-Antonio, Arnason, John Thor, Pandey, Siyaram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234676/
https://ncbi.nlm.nih.gov/pubmed/25401766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113250
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