Analysis of Ancestral and Functionally Relevant CD5 Variants in Systemic Lupus Erythematosus Patients

OBJECTIVE: CD5 plays a crucial role in autoimmunity and is a well-established genetic risk factor of developing RA. Recently, evidence of positive selection has been provided for the CD5 Pro224-Val471 haplotype in East Asian populations. The aim of the present work was to further analyze the functio...

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Pubblicato in:PLoS One
Autori principali: Cenit, Maria Carmen, Martínez-Florensa, Mario, Consuegra, Marta, Bonet, Lizette, Carnero-Montoro, Elena, Armiger, Noelia, Caballero-Baños, Miguel, Arias, Maria Teresa, Benitez, Daniel, Ortego-Centeno, Norberto, de Ramón, Enrique, Sabio, José Mario, García–Hernández, Francisco J., Tolosa, Carles, Suárez, Ana, González-Gay, Miguel A., Bosch, Elena, Martín, Javier, Lozano, Francisco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234640/
https://ncbi.nlm.nih.gov/pubmed/25402503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113090
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