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Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells.

To explore possible mechanisms by which complement membrane attack complexes (MAC) that are deposited in the glomerular mesangium might be pathogenic, we stimulated rat glomerular mesangial cells grown in vitro with nascent MACs formed from the purified human complement components C5b6 and normal hu...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Adler, S, Baker, P J, Johnson, R J, Ochi, R F, Pritzl, P, Couser, W G
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3005365/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112372
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