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Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

Neural stem cells are multipotent cells with the ability to differentiate into neurons, astrocytes, and oligodendrocytes. Lineage specification is strongly sensitive to the mechanical properties of the cellular environment. However, molecular pathways transducing matrix mechanical cues to intracellu...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Pathak, Medha M., Nourse, Jamison L., Tran, Truc, Hwe, Jennifer, Arulmoli, Janahan, Le, Dai Trang T., Bernardis, Elena, Flanagan, Lisa A., Tombola, Francesco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234578/
https://ncbi.nlm.nih.gov/pubmed/25349416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409802111
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