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Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

Neural stem cells are multipotent cells with the ability to differentiate into neurons, astrocytes, and oligodendrocytes. Lineage specification is strongly sensitive to the mechanical properties of the cellular environment. However, molecular pathways transducing matrix mechanical cues to intracellu...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Pathak, Medha M., Nourse, Jamison L., Tran, Truc, Hwe, Jennifer, Arulmoli, Janahan, Le, Dai Trang T., Bernardis, Elena, Flanagan, Lisa A., Tombola, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234578/
https://ncbi.nlm.nih.gov/pubmed/25349416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409802111
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