Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex

All organisms have evolved mechanisms to manage the stalling of ribosomes upon translation of aberrant mRNA. In eukaryotes, the large ribosomal subunit-associated quality control complex (RQC), composed of the listerin/Ltn1 E3 ubiquitin ligase and cofactors, mediates the ubiquitylation and extractio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lyumkis, Dmitry, Oliveira dos Passos, Dario, Tahara, Erich B., Webb, Kristofor, Bennett, Eric J., Vinterbo, Staal, Potter, Clinton S., Carragher, Bridget, Joazeiro, Claudio A. P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234556/
https://ncbi.nlm.nih.gov/pubmed/25349383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413882111
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