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Peptides with the Same Composition, Hydrophobicity, and Hydrophobic Moment Bind to Phospholipid Bilayers with Different Affinities

[Image: see text] We investigated the dependence of membrane binding on amino acid sequence for a series of amphipathic peptides derived from δ-lysin. δ-Lysin is a 26 amino acid, N-terminally formylated, hemolytic peptide that forms an amphipathic α-helix bound at membrane–water interfaces. A shorte...

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Veröffentlicht in:J Phys Chem B
Hauptverfasser: Cherry, Melissa A., Higgins, Sarah K., Melroy, Hilary, Lee, Hee-Seung, Pokorny, Antje
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234449/
https://ncbi.nlm.nih.gov/pubmed/25329983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp507289w
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