Coronary thrombolysis and infarct size reduction after intravenous infusion of recombinant tissue-type plasminogen activator in nonhuman primates.

Occlusive thrombus was produced by thrombin-induced coagulation in the left anterior descending coronary artery (LAD) of 16 open-chest baboons. In six control animals, occlusive thrombosis persisting over a period of 4 h as evidenced by coronary arteriography resulted in large transmural infarction...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Flameng, W, Van de Werf, F, Vanhaecke, J, Verstraete, M, Collen, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4038406/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111701
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