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Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism.

Metabolic acidosis is associated with enhanced renal ammonia-genesis which is regulated, in part, by glucocorticoids. The interaction between glucocorticoids and chronic metabolic acidosis on nitrogen utilization and muscle protein metabolism is unknown. In rats pair-fed by gavage, we found that chr...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: May, R C, Kelly, R A, Mitch, W E
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423396/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3511100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112344
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