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Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial

OBJECTIVE: To demonstrate the safety and effectiveness of responsive stimulation at the seizure focus as an adjunctive therapy to reduce the frequency of seizures in adults with medically intractable partial onset seizures arising from one or two seizure foci. METHODS: Randomized multicenter double-...

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Pubblicato in:Epilepsia
Autori principali: Heck, Christianne N, King-Stephens, David, Massey, Andrew D, Nair, Dileep R, Jobst, Barbara C, Barkley, Gregory L, Salanova, Vicenta, Cole, Andrew J, Smith, Michael C, Gwinn, Ryder P, Skidmore, Christopher, Van Ness, Paul C, Bergey, Gregory K, Park, Yong D, Miller, Ian, Geller, Eric, Rutecki, Paul A, Zimmerman, Richard, Spencer, David C, Goldman, Alica, Edwards, Jonathan C, Leiphart, James W, Wharen, Robert E, Fessler, James, Fountain, Nathan B, Worrell, Gregory A, Gross, Robert E, Eisenschenk, Stephan, Duckrow, Robert B, Hirsch, Lawrence J, Bazil, Carl, O'Donovan, Cormac A, Sun, Felice T, Courtney, Tracy A, Seale, Cairn G, Morrell, Martha J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233950/
https://ncbi.nlm.nih.gov/pubmed/24621228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12534
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