Reconstruction of platelet proteins into phospholipid vesicles. Functional proteoliposomes.

Platelet membrane glycoproteins IIb and IIIa were reconstituted into liposomes containing phosphatidylcholine. The reconstituted vesicles bound antiplatelet antibodies and showed specific binding to thrombin-activated platelets. Prostacyclin, a known inhibitor of thrombin-activated platelet aggregat...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Baldassare, J J, Kahn, R A, Knipp, M A, Newman, P J
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1985
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3155527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111693
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