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Computing limits on medicine risks based on collections of individual case reports

BACKGROUND: Quantifying a medicine’s risks for adverse effects is crucial in assessing its value as a therapeutic agent. Rare adverse effects are often not detected until after the medicine is marketed and used in large and heterogeneous patient populations, and risk quantification is even more diff...

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Publicat a:Theor Biol Med Model
Autors principals: Caster, Ola, Norén, G Niklas, Edwards, I Ralph
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233652/
https://ncbi.nlm.nih.gov/pubmed/24661640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-15
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