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Impact of upstream and downstream constraints on a signaling module’s ultrasensitivity

Much work has been done on the study of the biochemical mechanisms that result in ultrasensitive behavior of simple biochemical modules. However, in a living cell, such modules are embedded in a bigger network that constrains the range of inputs that the module will receive as well as the range of t...

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Vydáno v:Phys Biol
Hlavní autoři: Altszyler, Edgar, Ventura, Alejandra, Colman-Lerner, Alejandro, Chernomoretz, Ariel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233326/
https://ncbi.nlm.nih.gov/pubmed/25313165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/11/6/066003
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