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Enhanced breast cancer cell adherence to the lung endothelium via PAF acetylhydrolase inhibition: a potential mechanism for enhanced metastasis in smokers

Cancer deaths are primarily caused by distant metastases, rather than by primary tumor growth; however, the role of smoking in metastasis remains unclear. We demonstrated previously that endothelial cell platelet-activating factor (PAF) production results in enhanced inflammatory cell recruitment to...

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Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Kispert, Shannon E., Marentette, John O., McHowat, Jane
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233261/
https://ncbi.nlm.nih.gov/pubmed/25186013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00218.2014
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