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Nephritogenicity of antibodies to proteoglycans of the glomerular basement membrane--I.

We investigated nephritogenic potential of antibodies to heparan sulfate-proteoglycan of glomerular basement membrane. Glomeruli were isolated, basement membranes were prepared, proteoglycans extracted, and purified core protein was obtained. We immunized rabbits with the core protein, IgG fraction...

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Pubblicato in:J Clin Invest
Autori principali: Makino, H, Gibbons, J T, Reddy, M K, Kanwar, Y S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423320/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2935558/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112269
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