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RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner

Mechanisms of neuroendocrine tumor (NET) proliferation are poorly understood and therapies that effectively control NET progression and metastatic disease are limited. We found amplification of a putative oncogene, RABL6A, in primary human pancreatic NETs(PNETs) that correlated with high level RABL6...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Hagen, Jussara, Muniz, Viviane P., Falls, Kelly, Reed, Sara M., Taghiyev, Agshin F., Quelle, Frederick W., Gourronc, Francoise, Klingelhutz, Aloysius J., Major, Heather J., Askeland, Ryan, Sherman, Scott K., O'Dorisio, Thomas M., Bellizzi, Andrew M., Howe, James R., Darbro, Benjamin W., Quelle, Dawn E.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233153/
https://ncbi.nlm.nih.gov/pubmed/25273089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3742
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